Hematology System

Hematology Clinical Pathologic Correlation

Study key concepts of clinical pathologic correlation of hematology, including definitions, causes, and symptoms of hematopoiesis, splenomegaly, lymphadenopathy, bacteremia, and sepsis.

Investigation of Anemia

This lesson reviews the investigation of anemia by covering the definition, classification, signs, causes, and symptoms of microcytic anemia, normocytic anemia, and macrocytic anemia. Also explained are the Coombs test, reticulocyte count, and why serum methylmalonic acid is used as the diagnostic test in Vitamin B12 evaluation.

Structure & Regulation

This lesson reviews the structure and regulation of the hematologic system. Bone marrow architecture, hematopoiesis, and erythropoiesis are reviewed.

Bleeding Disorders

Learn a doctor’s approach to bleeding disorders and learn key hematologic concepts of blood platelet disorders, immune thrombocytopenia (ITP), heparin-induced thrombocytopenia (HIT), and Von Willebrand Disease (vWD). Also reviewed are non-steroidal anti-inflammatory drugs, consumptive coagulopathy, hypersplenism, and hemophilia A.

Hemostasis & Testing

This lesson presents an overview of the pathophysiology and pharmacology of hemostasis, including formation of the platelet plug, clot propagation & the coagulation cascade, regulation of clotting, and fibrinolysis. Also reviewed are presentations of bleeding disorders, including lab testing of platelet count, bleeding time, and prothrombin time.

Procoagulant States

This lesson reviews procoagulant states and thromboembolic disease, including the mechanisms of actions of anti-platelet and anti-coagulation factors, Virchow’s triangle, anti-phospholipid syndrome, deep vein thrombosis, and pulmonary embolism. Learn the clinical approach to hereditary and acquired diseases of thrombosis such that you can describe their diagnosis, pathophysiology, presentation and treatment.