Active and Passive Immunotherapy Quiz

A 50-year-old male presents for a well-patient check-up.  He has a history of well-controlled hypertension.  He does not smoke and says he drinks alcohol only occasionally.  Physical examination is unremarkable.  He plans to take a 2-week vacation in Mexico next month.  Which of the following vaccinations would be recommended at this time?

The adult PPV vaccine contains 23 serotypes of Streptococcus pneumoniae capsular material plus an adjuvant.  What is the purpose of addition of an adjuvant?

A patient being studied for an unusual immunologic disorder is found to lack class I MHC molecules, and homogenized lymphocyte precipitates are found to lack TAP1 molecules. Which of the following vaccines would most likely be ineffective in this patient?

The vaccine produced by the military for protection of recruits against respiratory adenovirus strains is non-attenuated and delivered orally via enteric coated capsule.  What advantage does this have over injection of a killed viral vaccine?

A 3-month-old infant is brought into the emergency department, coughing and unable to catch his breath. His parents state that the symptoms developed quickly; they also note the infant was born prematurely. Auscultation reveals wheezing. As part of a research study, a medical student obtains a chest X-ray, which shows perihilar fullness, and collects some of the infant’s oral secretions and studies them under a microscope, observing several cells with multiple nuclei.  If the ultimate goal of this study were to develop a vaccine against this agent, which of the following would most likely be true of that vaccine?